Detalhe da pesquisa
1.
A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action.
Cell
; 177(6): 1649-1661.e9, 2019 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31080069
2.
AMPD2 regulates GTP synthesis and is mutated in a potentially treatable neurodegenerative brainstem disorder.
Cell
; 154(3): 505-17, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23911318
3.
OpenMS 3 enables reproducible analysis of large-scale mass spectrometry data.
Nat Methods
; 21(3): 365-367, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38366242
4.
Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells.
Mol Cell
; 55(2): 253-63, 2014 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-24882210
5.
SmartPeak Automates Targeted and Quantitative Metabolomics Data Processing.
Anal Chem
; 92(24): 15968-15974, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33269929
6.
Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism.
PLoS Comput Biol
; 15(6): e1007066, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31158228
7.
RapidRIP quantifies the intracellular metabolome of 7 industrial strains of E. coli.
Metab Eng
; 47: 383-392, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29702276
8.
Adaptation to the coupling of glycolysis to toxic methylglyoxal production in tpiA deletion strains of Escherichia coli requires synchronized and counterintuitive genetic changes.
Metab Eng
; 48: 82-93, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29842925
9.
Adaptive laboratory evolution resolves energy depletion to maintain high aromatic metabolite phenotypes in Escherichia coli strains lacking the Phosphotransferase System.
Metab Eng
; 48: 233-242, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29906504
10.
Multiple Optimal Phenotypes Overcome Redox and Glycolytic Intermediate Metabolite Imbalances in Escherichia coli pgi Knockout Evolutions.
Appl Environ Microbiol
; 84(19)2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30054360
11.
Quantifying the Metabolome of Pseudomonas taiwanensis VLB120: Evaluation of Hot and Cold Combined Quenching/Extraction Approaches.
Anal Chem
; 89(17): 8738-8747, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28727413
12.
MID Max: LC-MS/MS Method for Measuring the Precursor and Product Mass Isotopomer Distributions of Metabolic Intermediates and Cofactors for Metabolic Flux Analysis Applications.
Anal Chem
; 88(2): 1362-70, 2016 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26666286
13.
Modeling Method for Increased Precision and Scope of Directly Measurable Fluxes at a Genome-Scale.
Anal Chem
; 88(7): 3844-52, 2016 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26981784
14.
Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli.
Mol Syst Biol
; 9: 661, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23632383
15.
A model-driven quantitative metabolomics analysis of aerobic and anaerobic metabolism in E. coli K-12 MG1655 that is biochemically and thermodynamically consistent.
Biotechnol Bioeng
; 111(4): 803-15, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24249002
16.
In Search of Disentanglement in Tandem Mass Spectrometry Datasets.
Biomolecules
; 13(9)2023 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37759743
17.
Automating the design-build-test-learn cycle towards next-generation bacterial cell factories.
N Biotechnol
; 74: 1-15, 2023 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36736693
18.
An automated workflow for multi-omics screening of microbial model organisms.
NPJ Syst Biol Appl
; 9(1): 14, 2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37208327
19.
Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans.
NPJ Aging
; 9(1): 7, 2023 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37012386
20.
A Comprehensive Evaluation of Metabolomics Data Preprocessing Methods for Deep Learning.
Metabolites
; 12(3)2022 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35323644